March 9, 2011

University Hospitals tests experimental HIV vaccine


12:05 AM, Mar 9, 2011
Written by Monica Robins

CLEVELAND -- The Case Western Reserve University/University Hospitals AIDS Clinical Trials Unit is now screening potential participants for a nationwide HIV vaccine clinical trial (HVTN505) being conducted by the HIV Vaccine Trials Network.

The HIV vaccine trial is the first of its kind in Cleveland since 2003.

The trial is testing the safety and effectiveness of a combination of two HIV vaccines to see if they will stimulate an immune response to HIV or decrease the amount of virus in the blood if a person later becomes infected.

Neither vaccine can cause HIV infection.

The trial, which also is open in 15 other U.S. cities, is looking to enroll 1,350 gay men and transgender women. Participants must be 18-50 years old and HIV-uninfected (negative).

People interested in learning more about the vaccine trial should call 216-844-4444.

The vaccine trial comes to Cleveland after a year of promising developments in the worldwide search for effective new tools to help stem the AIDS epidemic, now entering its third decade.

Last year, clinical trials proved some level of effectiveness for two HIV prevention strategies. The CAPRISA004 study demonstrated for the first time that a microbicide - a gel used by a woman prior to sexual activity, could reduce a woman's risk of acquiring HIV.

Another clinical trial showed that antiretroviral drugs - used to treat people living with HIV - can reduce a person's risk of acquiring HIV if used consistently prior to sexual contact.

The Case Western Reserve/UH AIDS Clinical Trials Unit has been conducting AIDS-related clinical research since its founding in 1987.

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